By Jim Ellis — Monday, April 6, 2026
Senate
Louisiana Sen. Bill Cassidy (R)
According to the American Pulse data, Sen. Cassidy would be in danger of not even advancing to a runoff against Rep. Julia Letlow (R-Start) and State Treasurer and former Rep. John Fleming. In hypothetical runoff pairings, should Sen. Cassidy rebound, he would individually trail both Letlow and Fleming.
The American Pulse poll (March 20-24; 455 likely Louisiana Republican primary voters) sees Rep. Letlow topping Fleming and Sen. Cassidy, 31-25-21 percent, respectively. In a potential runoff, Rep. Letlow would lead Fleming, 37-34 percent. With 29 percent of the respondents unsure about this race, such a contest would be rated as too close to call.
Paired with incumbent Cassidy, Rep. Letlow would defeat him by a whopping 30 points according to this respondent sample, 54-24 percent. Fleming fares almost as well against the Senator. In a Fleming-Cassidy runoff, the challenger would lead the incumbent, 49-29 percent.
With a sample size of only 455 individuals for a statewide survey, the error factor would be high because of the small universe. These results, however, are so lopsided that even a wide error margin would still send Cassidy packing particularly because he fares so poorly in a runoff against either opponent.
Sen. Cassidy is facing serious obstacles. Obviously, these polling numbers reveal that the Senator is not popular within the Louisiana conservative vote base. Secondly, his vote to impeach President Trump associated with the January 6th conflict at the Capitol obviously put him at odds with the chief executive, though it is likely that the Senator believed doing so would not cause him future political problems because he obviously believed that Trump would never return to the White House.
As a result, President Trump has already endorsed Rep. Letlow, doing so even before she became an official Senate candidate.
Perhaps Sen. Cassidy’s most serious problem, however, is Louisiana’s new nomination structure for federal offices. Since the 1970s, Louisiana has featured a jungle qualification format for all offices. All candidates are placed on the same ballot in an election concurrent with the regular general election. If a candidate records majority support in the first vote, the individual is elected. If not, the top two finishers regardless of political party affiliation advanced to a post-general election runoff.
Under the new Louisiana primary system effective with the 2026 election, registered party members may only vote in their own party primary. If a person is registered as a “No Party” voter, the individual may choose a primary ballot at the polling place. Once selected, the “No Party” voter can then only participate in an associated runoff of the party in which he or she chose for the regular primary election.
In the jungle system, and particularly because the Democrats are currently very weak in Louisiana, Sen. Cassidy was able to attract a segment of their votes. This made him stronger in seeking re-election. In 2026, Democrats will not be allowed to crossover into the Republican primary, just as Republicans will not be allowed to vote in any 2026 Democratic primary.
Therefore, the new partisan primary system gives the Cassidy challengers a boost because endorsements, such as the one from President Trump, will carry more weight within the conservative Republican vote base without any adverse boomerang effect coming from crossover Democrats.
Added together, these obstacles spell trouble for Sen. Cassidy’s re-election chances as the current polls reflect.
The small sample American Pulse survey may not be completely indicative of where the entire Louisiana Republican electorate stands, but the Senator has fared poorly in other statewide polls, as well.
Looking at the last six publicly released Republican primary studies since Feb. 24, Sen. Cassidy has averaged only 26.7 percent support in the surveys testing a three-way contest among the Senator, Rep. Letlow, and Fleming.
As we head toward a May 16 Louisiana Republican primary election and a potential June 27 GOP runoff, Sen. Cassidy today looks to be the Senate incumbent most likely to fail to qualify for the general election.